Nucleomorphs, relic endosymbiont nuclei, have been studied as a model to elucidate the evolutionary process of integrating a eukaryotic endosymbiont into a host cell organelle.Recently, we reported two new dinoflagellates possessing nucleomorphs, and proposed them as new models in this research field based on the following findings: genome integrat
MicroRNAs (miRNAs) are endogenously expressed noncoding RNA molecules that are believed to regulate multiple neurobiological processes.Expression studies have revealed distinct temporal expression patterns in the developing rodent and porcine brain, but comprehensive profiling in the developing human brain has 2D Crystal Photo not been previously r
Abstract Background Targeting glucose uptake by glucose transporter (GLUT) inhibitors is a therapeutic opportunity, but efforts on GLUT inhibitors have not been successful in the clinic and the underlying mechanism remains unclear.We aim to identify the key metabolic changes responsible for cancer cell survival from glucose limitation and elucidate
Background: There is increasing interest in investigating genetic risk models in empirical studies, but such studies are premature when the Support expected predictive ability of the risk model is low.We assessed how accurately the predictive ability of genetic risk models can be estimated in simulated data that are created based on the odds ratios
Yogesh Dwivedi, Ghanshyam N PandeyPsychiatric Institute, Department of Psychiatry, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USAAbstract: Mood disorders are among the most prevalent and recurrent forms of psychiatric illnesses.In the last decade, there has been increased understanding of the biological basis o